Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM50074778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074778 (2-Phenyl-quinoline-4-carboxylic acid (methylcarbam...) Show SMILES CNC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H21N3O2/c1-26-25(30)23(18-12-6-3-7-13-18)28-24(29)20-16-22(17-10-4-2-5-11-17)27-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,26,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074778 (2-Phenyl-quinoline-4-carboxylic acid (methylcarbam...) Show SMILES CNC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H21N3O2/c1-26-25(30)23(18-12-6-3-7-13-18)28-24(29)20-16-22(17-10-4-2-5-11-17)27-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,26,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL					Assay Description Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma counting				J Med Chem 53: 8080-8 (2010) Article DOI: 10.1021/jm1010012 BindingDB Entry DOI: 10.7270/Q2736R5F
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074778 (2-Phenyl-quinoline-4-carboxylic acid (methylcarbam...) Show SMILES CNC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H21N3O2/c1-26-25(30)23(18-12-6-3-7-13-18)28-24(29)20-16-22(17-10-4-2-5-11-17)27-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,26,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Binding affinity to human NK3 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 7405-11 (2011) Article DOI: 10.1016/j.bmcl.2011.10.014 BindingDB Entry DOI: 10.7270/Q2CC11Z5
					More data for this Ligand-Target Pair