Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM50074801'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074801 (3-Phenyl-3-[(2-phenyl-quinoline-4-carbonyl)-amino]...) Show SMILES COC(=O)CC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H22N2O3/c1-31-25(29)17-24(19-12-6-3-7-13-19)28-26(30)21-16-23(18-10-4-2-5-11-18)27-22-15-9-8-14-20(21)22/h2-16,24H,17H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	973	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074801 (3-Phenyl-3-[(2-phenyl-quinoline-4-carbonyl)-amino]...) Show SMILES COC(=O)CC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H22N2O3/c1-31-25(29)17-24(19-12-6-3-7-13-19)28-26(30)21-16-23(18-10-4-2-5-11-18)27-22-15-9-8-14-20(21)22/h2-16,24H,17H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL					Assay Description Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma counting				J Med Chem 53: 8080-8 (2010) Article DOI: 10.1021/jm1010012 BindingDB Entry DOI: 10.7270/Q2736R5F
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074801 (3-Phenyl-3-[(2-phenyl-quinoline-4-carbonyl)-amino]...) Show SMILES COC(=O)CC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H22N2O3/c1-31-25(29)17-24(19-12-6-3-7-13-19)28-26(30)21-16-23(18-10-4-2-5-11-18)27-22-15-9-8-14-20(21)22/h2-16,24H,17H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Binding affinity to human NK3 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 7405-11 (2011) Article DOI: 10.1016/j.bmcl.2011.10.014 BindingDB Entry DOI: 10.7270/Q2CC11Z5
					More data for this Ligand-Target Pair