BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50173950'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50173950
PNG
(5-(2-Chloro-phenyl)-thiophene-2-carboxylic acid (1...)
Show SMILES Clc1ccccc1-c1ccc(s1)C(=O)NC1CN2CCC1CC2 |THB:14:15:21.22:19.18,(6.36,-3.68,;6.75,-5.17,;8.23,-5.58,;8.62,-7.09,;7.52,-8.16,;6.03,-7.74,;5.66,-6.24,;4.17,-5.82,;2.97,-6.78,;1.68,-5.93,;2.1,-4.45,;3.63,-4.38,;1.14,-3.23,;1.71,-1.81,;-.39,-3.46,;-1.33,-2.24,;-1.63,-.84,;-2.97,-.23,;-2.91,1.4,;-2.45,.3,;-2.7,-1.6,;-4.24,-2.27,;-4.45,-.89,)|
Show InChI InChI=1S/C18H19ClN2OS/c19-14-4-2-1-3-13(14)16-5-6-17(23-16)18(22)20-15-11-21-9-7-12(15)8-10-21/h1-6,12,15H,7-11H2,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 525n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitine

Bioorg Med Chem Lett 15: 4727-30 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.070
BindingDB Entry DOI: 10.7270/Q28K79W0
More data for this
Ligand-Target Pair