Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 4' and Ligand = 'BDBM50542858'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542858 (CHEMBL4649438) Show SMILES CC(C)C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C27H47N11O5/c1-15(2)13-21(38-23(41)18(28)5-3-11-34-26(30)31)25(43)36-19(6-4-12-35-27(32)33)24(42)37-20(22(29)40)14-16-7-9-17(39)10-8-16/h7-10,15,18-21,39H,3-6,11-14,28H2,1-2H3,(H2,29,40)(H,36,43)(H,37,42)(H,38,41)(H4,30,31,34)(H4,32,33,35)/t18-,19+,20+,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542858 (CHEMBL4649438) Show SMILES CC(C)C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C27H47N11O5/c1-15(2)13-21(38-23(41)18(28)5-3-11-34-26(30)31)25(43)36-19(6-4-12-35-27(32)33)24(42)37-20(22(29)40)14-16-7-9-17(39)10-8-16/h7-10,15,18-21,39H,3-6,11-14,28H2,1-2H3,(H2,29,40)(H,36,43)(H,37,42)(H,38,41)(H4,30,31,34)(H4,32,33,35)/t18-,19+,20+,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542858 (CHEMBL4649438) Show SMILES CC(C)C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C27H47N11O5/c1-15(2)13-21(38-23(41)18(28)5-3-11-34-26(30)31)25(43)36-19(6-4-12-35-27(32)33)24(42)37-20(22(29)40)14-16-7-9-17(39)10-8-16/h7-10,15,18-21,39H,3-6,11-14,28H2,1-2H3,(H2,29,40)(H,36,43)(H,37,42)(H,38,41)(H4,30,31,34)(H4,32,33,35)/t18-,19+,20+,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542858 (CHEMBL4649438) Show SMILES CC(C)C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C27H47N11O5/c1-15(2)13-21(38-23(41)18(28)5-3-11-34-26(30)31)25(43)36-19(6-4-12-35-27(32)33)24(42)37-20(22(29)40)14-16-7-9-17(39)10-8-16/h7-10,15,18-21,39H,3-6,11-14,28H2,1-2H3,(H2,29,40)(H,36,43)(H,37,42)(H,38,41)(H4,30,31,34)(H4,32,33,35)/t18-,19+,20+,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542858 (CHEMBL4649438) Show SMILES CC(C)C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C27H47N11O5/c1-15(2)13-21(38-23(41)18(28)5-3-11-34-26(30)31)25(43)36-19(6-4-12-35-27(32)33)24(42)37-20(22(29)40)14-16-7-9-17(39)10-8-16/h7-10,15,18-21,39H,3-6,11-14,28H2,1-2H3,(H2,29,40)(H,36,43)(H,37,42)(H,38,41)(H4,30,31,34)(H4,32,33,35)/t18-,19+,20+,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542858 (CHEMBL4649438) Show SMILES CC(C)C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C27H47N11O5/c1-15(2)13-21(38-23(41)18(28)5-3-11-34-26(30)31)25(43)36-19(6-4-12-35-27(32)33)24(42)37-20(22(29)40)14-16-7-9-17(39)10-8-16/h7-10,15,18-21,39H,3-6,11-14,28H2,1-2H3,(H2,29,40)(H,36,43)(H,37,42)(H,38,41)(H4,30,31,34)(H4,32,33,35)/t18-,19+,20+,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair