Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neutrophil collagenase' and Ligand = 'BDBM50077443'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50077443 ((R)-5-(4-Methoxy-benzenesulfonyl)-4,5,6,7-tetrahyd...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2[nH]cnc2C[C@@H]1C(=O)NO Show InChI InChI=1S/C14H16N4O5S/c1-23-9-2-4-10(5-3-9)24(21,22)18-7-12-11(15-8-16-12)6-13(18)14(19)17-20/h2-5,8,13,20H,6-7H2,1H3,(H,15,16)(H,17,19)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]				J Med Chem 42: 1908-20 (1999) Article DOI: 10.1021/jm980631s BindingDB Entry DOI: 10.7270/Q2251JV5
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50077443 ((R)-5-(4-Methoxy-benzenesulfonyl)-4,5,6,7-tetrahyd...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2[nH]cnc2C[C@@H]1C(=O)NO Show InChI InChI=1S/C14H16N4O5S/c1-23-9-2-4-10(5-3-9)24(21,22)18-7-12-11(15-8-16-12)6-13(18)14(19)17-20/h2-5,8,13,20H,6-7H2,1H3,(H,15,16)(H,17,19)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)				J Med Chem 42: 4506-23 (1999) BindingDB Entry DOI: 10.7270/Q22J6B22
					More data for this Ligand-Target Pair