Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil collagenase (Homo sapiens (Human)) | BDBM50225397![]() ((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster Curated by ChEMBL | Assay Description Inhibition of MMP8 | J Med Chem 50: 5752-64 (2007) Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM50225397![]() ((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Inhibition of MMP-8 (unknown origin) | J Med Chem 56: 6858-70 (2013) Article DOI: 10.1021/jm4006753 BindingDB Entry DOI: 10.7270/Q2TF018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM50225397![]() ((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba... | J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT | |||||||||||
More data for this Ligand-Target Pair |