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Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil cytosol factor 1' and Ligand = 'BDBM50520356'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil cytosol factor 1


(Homo sapiens)		BDBM50520356
PNG
(CHEMBL4465101)
Show SMILES COc1ccc(CNc2cc(N)nc3ccccc23)cc1
Show InChI InChI=1S/C17H17N3O/c1-21-13-8-6-12(7-9-13)11-19-16-10-17(18)20-15-5-3-2-4-14(15)16/h2-10H,11H2,1H3,(H3,18,19,20)
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MMDB

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PC cid
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Article
PubMed
 2.43E+5n/an/an/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...

J Med Chem 63: 1156-1177 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01492
BindingDB Entry DOI: 10.7270/Q2TQ64XB
More data for this
Ligand-Target Pair