Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM211470'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM211470 (US9290457, Example 1.12) Show SMILES CN1C(C(C(C)=O)=C(C)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1C(=O)N1CC(O)C1)C#N |t:6| Show InChI InChI=1S/C26H23F3N4O4/c1-14-22(15(2)34)23(20-8-7-16(11-30)9-21(20)24(36)32-12-19(35)13-32)31(3)25(37)33(14)18-6-4-5-17(10-18)26(27,28)29/h4-10,19,23,35H,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9290457 (2016) BindingDB Entry DOI: 10.7270/Q2QJ7G4W
					More data for this Ligand-Target Pair