Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM211902'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM211902 (US9290459, 47.17 | US9670166, 47.17) Show SMILES CS(=O)(=O)c1cc(ccc1[C@H]1N(C(=O)NCC2(O)CCC2)C(=O)N(C2=C1C(=O)CC2)c1cccc(c1)C(F)(F)F)C#N |r,c:26| Show InChI InChI=1S/C28H25F3N4O6S/c1-42(40,41)22-12-16(14-32)6-7-19(22)24-23-20(8-9-21(23)36)34(18-5-2-4-17(13-18)28(29,30)31)26(38)35(24)25(37)33-15-27(39)10-3-11-27/h2,4-7,12-13,24,39H,3,8-11,15H2,1H3,(H,33,37)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9670166 (2017) BindingDB Entry DOI: 10.7270/Q25Q4T8F
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM211902 (US9290459, 47.17 | US9670166, 47.17) Show SMILES CS(=O)(=O)c1cc(ccc1[C@H]1N(C(=O)NCC2(O)CCC2)C(=O)N(C2=C1C(=O)CC2)c1cccc(c1)C(F)(F)F)C#N |r,c:26| Show InChI InChI=1S/C28H25F3N4O6S/c1-42(40,41)22-12-16(14-32)6-7-19(22)24-23-20(8-9-21(23)36)34(18-5-2-4-17(13-18)28(29,30)31)26(38)35(24)25(37)33-15-27(39)10-3-11-27/h2,4-7,12-13,24,39H,3,8-11,15H2,1H3,(H,33,37)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9290459 (2016) BindingDB Entry DOI: 10.7270/Q2KS6QD5
					More data for this Ligand-Target Pair