Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM398288'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398288 (US10323018, Compound I-17) Show SMILES CC(C)Oc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O2/c1-16(2)32-23-15-21(17-5-8-19(26)9-6-17)30-22-14-18(7-10-20(22)23)25(31)29-11-3-4-24-27-12-13-28-24/h5-10,12-16H,3-4,11H2,1-2H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
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