Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM398318'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398318 (US10323018, Compound I-47) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1ccc(cc1)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C27H22FN3O2/c1-2-33-26-16-24(20-7-10-22(28)11-8-20)31-25-15-21(9-12-23(25)26)27(32)30-14-13-18-3-5-19(17-29)6-4-18/h3-12,15-16H,2,13-14H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
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