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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM50095304'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nitric oxide synthase, endothelial


(Bos taurus (bovine))		BDBM50095304
PNG
(CHEMBL3589093)
Show SMILES CC(=N)NCc1cccc(CN(Cc2ccc(cc2)[N+]([O-])=O)Cc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C24H25N5O4/c1-18(25)26-14-21-3-2-4-22(13-21)17-27(15-19-5-9-23(10-6-19)28(30)31)16-20-7-11-24(12-8-20)29(32)33/h2-13H,14-17H2,1H3,(H2,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



University of Chieti"G. d'Annunzio"

Curated by ChEMBL


Assay Description
Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analys...

ACS Med Chem Lett 6: 635-40 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00149
BindingDB Entry DOI: 10.7270/Q2C53NKC
More data for this
Ligand-Target Pair