Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM50141078'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50141078 (6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-naphthal...) Show SMILES CN1CCN(CCOc2ccc(-c3cccc(N)n3)c3ccccc23)CC1 Show InChI InChI=1S/C22H26N4O/c1-25-11-13-26(14-12-25)15-16-27-21-10-9-18(17-5-2-3-6-19(17)21)20-7-4-8-22(23)24-20/h2-10H,11-16H2,1H3,(H2,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description In vitro inhibition of human endothelial nitric oxide synthase				J Med Chem 47: 1575-86 (2004) Article DOI: 10.1021/jm030519g BindingDB Entry DOI: 10.7270/Q2J102MT
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