Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM50341678![]() (6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California, Irvine | Assay Description Inhibition assay using nitric oxide synthases. | Biochemistry 49: 10803-10 (2010) Article DOI: 10.1021/bi1013479 BindingDB Entry DOI: 10.7270/Q2KS6Q51 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, endothelial (Bos taurus (bovine)) | BDBM50341678![]() (6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysis | J Med Chem 54: 2039-48 (2011) Article DOI: 10.1021/jm101071n BindingDB Entry DOI: 10.7270/Q2571CB0 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, endothelial (Bos taurus (bovine)) | BDBM50341678![]() (6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of bovine eNOS | J Med Chem 58: 994-1004 (2015) Article DOI: 10.1021/jm501723p BindingDB Entry DOI: 10.7270/Q2833TP5 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |