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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM50403159'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nitric oxide synthase, endothelial


(Bos taurus (bovine))		BDBM50403159
PNG
(CHEMBL4173076)
Show SMILES Cl.Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)Cc2cnc[nH]2)c1 |r|
Show InChI InChI=1S/C17H28O6P2S/c1-13(2)6-5-7-14(3)8-16-9-15(4)17(26-16)10-23-11-24(18,19)12-25(20,21)22/h6,8-9H,5,7,10-12H2,1-4H3,(H,18,19)(H2,20,21,22)/b14-8+
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PC cid
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Similars
Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



University of Chieti "G. d'Annunzio"

Curated by ChEMBL


Assay Description
Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...

Eur J Med Chem 152: 53-64 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.027
BindingDB Entry DOI: 10.7270/Q2C2500M
More data for this
Ligand-Target Pair