Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM469437'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM469437 (US10807988, Example SC_3078 | cis-5-[1-(Cyclobutyl...) Show SMILES CN(C)[C@]1(CC[C@]2(CN(C(=O)N2CC2CCC2)c2cnc(cc2C)C#N)CC1)c1ccccc1 |r,wU:6.11,3.2,(4.01,24.08,;4.78,22.75,;6.32,22.75,;4.01,21.41,;3.24,20.08,;1.7,20.08,;.93,21.41,;.03,22.66,;-1.44,22.18,;-1.44,20.64,;-2.68,19.74,;.03,20.17,;.5,18.7,;-.53,17.56,;-2.07,17.56,;-2.07,16.02,;-.53,16.02,;-2.53,23.27,;-4.01,22.87,;-5.1,23.96,;-4.7,25.45,;-3.22,25.85,;-2.13,24.76,;-.64,25.16,;-5.79,26.54,;-6.88,27.63,;1.7,22.75,;3.24,22.75,;4.78,20.08,;4.01,18.74,;4.78,17.41,;6.32,17.41,;7.09,18.74,;6.32,20.08,)| Show InChI InChI=1S/C28H35N5O/c1-21-16-24(17-29)30-18-25(21)32-20-27(33(26(32)34)19-22-8-7-9-22)12-14-28(15-13-27,31(2)3)23-10-5-4-6-11-23/h4-6,10-11,16,18,22H,7-9,12-15,19-20H2,1-3H3/t27-,28+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Grünenthal GmbH US Patent					Assay Description The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...				US Patent US10807988 (2020) BindingDB Entry DOI: 10.7270/Q25Q5060
					More data for this Ligand-Target Pair