Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM469459'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM469459 (US10807988, Example SC_3101 | cis-1-[(1-Hydroxy-cy...) Show SMILES CN[C@]1(CC[C@]2(CN(C(=O)N2CC2(O)CCC2)c2cnc(nc2)N2CCN(C)CC2)CC1)c1ccccc1 |r,wU:5.10,2.1,(4.75,23.16,;5.52,21.83,;4.75,20.49,;3.98,19.16,;2.44,19.16,;1.67,20.49,;.76,21.74,;-.7,21.26,;-.7,19.72,;-1.95,18.82,;.76,19.25,;1.24,17.78,;.21,16.64,;1.7,16.24,;-1.33,16.64,;-1.33,15.1,;.21,15.1,;-1.88,22.26,;-3.33,21.73,;-4.5,22.73,;-4.23,24.24,;-2.78,24.76,;-1.61,23.77,;-5.41,25.24,;-5.14,26.75,;-6.31,27.74,;-7.76,27.22,;-8.94,28.22,;-8.03,25.71,;-6.86,24.71,;2.44,21.83,;3.98,21.83,;5.52,19.16,;4.75,17.82,;5.52,16.49,;7.06,16.49,;7.83,17.82,;7.06,19.16,)| Show InChI InChI=1S/C29H41N7O2/c1-30-29(23-7-4-3-5-8-23)13-11-27(12-14-29)21-35(26(37)36(27)22-28(38)9-6-10-28)24-19-31-25(32-20-24)34-17-15-33(2)16-18-34/h3-5,7-8,19-20,30,38H,6,9-18,21-22H2,1-2H3/t27-,29+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Grünenthal GmbH US Patent					Assay Description The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...				US Patent US10807988 (2020) BindingDB Entry DOI: 10.7270/Q25Q5060
					More data for this Ligand-Target Pair