Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50200591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50200591 (CHEMBL238819 | N-cyclobutyl-2-(3-{1-[3-(5-methoxy-...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC3CCC3)c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C32H44N4O4/c1-22(2)29(40-30-20-26(39-4)13-12-23(30)3)16-19-34-17-14-25(15-18-34)36-28-11-6-5-10-27(28)35(32(36)38)21-31(37)33-24-8-7-9-24/h5-6,10-13,20,22,24-25,29H,7-9,14-19,21H2,1-4H3,(H,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50200591 (CHEMBL238819 | N-cyclobutyl-2-(3-{1-[3-(5-methoxy-...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC3CCC3)c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C32H44N4O4/c1-22(2)29(40-30-20-26(39-4)13-12-23(30)3)16-19-34-17-14-25(15-18-34)36-28-11-6-5-10-27(28)35(32(36)38)21-31(37)33-24-8-7-9-24/h5-6,10-13,20,22,24-25,29H,7-9,14-19,21H2,1-4H3,(H,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair