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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50200619'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50200619
PNG
(CHEMBL240298 | N-butyl-2-(3-{1-[3-(5-methoxy-2-met...)
Show SMILES CCCCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:22.23|
Show InChI InChI=1S/C32H46N4O4/c1-6-7-17-33-31(37)22-35-27-10-8-9-11-28(27)36(32(35)38)25-14-18-34(19-15-25)20-16-29(23(2)3)40-30-21-26(39-5)13-12-24(30)4/h8-13,21,23,25,29H,6-7,14-20,22H2,1-5H3,(H,33,37)
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Article
PubMed
 29n/an/an/an/an/an/an/an/a



Organon Laboratories Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs

Bioorg Med Chem 15: 1828-47 (2007)


Article DOI: 10.1016/j.bmc.2006.11.030
BindingDB Entry DOI: 10.7270/Q27S7NF2
More data for this
Ligand-Target Pair