Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TNK1' and Ligand = 'BDBM419727'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human))	BDBM419727 (US10464919, Example 65) Show SMILES Cc1cc(ccc1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C(=O)NC1CC1 Show InChI InChI=1S/C28H33N5O2/c1-18-15-20(27(34)30-21-6-7-21)5-9-25(18)33-13-11-32(12-14-33)17-19-4-8-22-24(16-19)31-28(35)23-3-2-10-29-26(22)23/h4-5,8-9,15-16,21,29H,2-3,6-7,10-14,17H2,1H3,(H,30,34)(H,31,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
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