Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TNK1' and Ligand = 'BDBM419785'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human))	BDBM419785 (US10464919, Example 123) Show SMILES O=c1[nH]c2cc(CN3CCN(CC3)c3ccc(nc3)C#N)ccc2c2NCCCc12 Show InChI InChI=1S/C23H24N6O/c24-13-17-4-5-18(14-26-17)29-10-8-28(9-11-29)15-16-3-6-19-21(12-16)27-23(30)20-2-1-7-25-22(19)20/h3-6,12,14,25H,1-2,7-11,15H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.92	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
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