Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM107149'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM107149 (US8592415, 34) Show SMILES OC1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22N4O2/c26-17-8-10-25(11-9-17)14-21(27)23-16-5-3-4-15(12-16)20-13-22-18-6-1-2-7-19(18)24-20/h1-7,12-13,17,26H,8-11,14H2,(H,23,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
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