Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM125910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM125910 (US8765727, 13) Show SMILES Clc1cnc2Nc3cccc(CCOc4cccc(CCCNc1n2)c4)c3 Show InChI InChI=1S/C21H21ClN4O/c22-19-14-24-21-25-17-7-1-4-16(12-17)9-11-27-18-8-2-5-15(13-18)6-3-10-23-20(19)26-21/h1-2,4-5,7-8,12-14H,3,6,9-11H2,(H2,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...				US Patent US8765727 (2014) BindingDB Entry DOI: 10.7270/Q2FQ9V87
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