Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM325479'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325479 ((S)-1-(2-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)...) Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCN2CC[C@H](O)C2)c1 |r| Show InChI InChI=1S/C23H30N8O/c1-3-19(4-2)30-14-18(12-26-30)23-22-5-7-24-31(22)16-21(27-23)17-11-25-29(13-17)10-9-28-8-6-20(32)15-28/h5,7,11-14,16,19-20,32H,3-4,6,8-10,15H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325479 ((S)-1-(2-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)...) Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCN2CC[C@H](O)C2)c1 |r| Show InChI InChI=1S/C23H30N8O/c1-3-19(4-2)30-14-18(12-26-30)23-22-5-7-24-31(22)16-21(27-23)17-11-25-29(13-17)10-9-28-8-6-20(32)15-28/h5,7,11-14,16,19-20,32H,3-4,6,8-10,15H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021) BindingDB Entry DOI: 10.7270/Q2T156RN
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325479 ((S)-1-(2-(4-(4-(1-(pentan-3- yl)-1H-pyrazol-4- yl)...) Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCN2CC[C@H](O)C2)c1 |r| Show InChI InChI=1S/C23H30N8O/c1-3-19(4-2)30-14-18(12-26-30)23-22-5-7-24-31(22)16-21(27-23)17-11-25-29(13-17)10-9-28-8-6-20(32)15-28/h5,7,11-14,16,19-20,32H,3-4,6,8-10,15H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020) BindingDB Entry DOI: 10.7270/Q2CC13R9
					More data for this Ligand-Target Pair