Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM330016'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM330016 (US10463675, Example 99 | US10980815, Ex. No. 99 | ...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@]12NC(=O)[C@@H]1CC1(F)F)c1nc(Nc2cnn(c2)C2COC2)ncc1F |r| Show InChI InChI=1S/C20H22F3N7O2/c1-10-14-6-29(9-19(10,14)28-17(31)13-2-20(13,22)23)16-15(21)4-24-18(27-16)26-11-3-25-30(5-11)12-7-32-8-12/h3-5,10,12-14H,2,6-9H2,1H3,(H,28,31)(H,24,26,27)/t10-,13+,14+,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...				US Patent US9663526 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KVD
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM330016 (US10463675, Example 99 | US10980815, Ex. No. 99 | ...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@]12NC(=O)[C@@H]1CC1(F)F)c1nc(Nc2cnn(c2)C2COC2)ncc1F |r| Show InChI InChI=1S/C20H22F3N7O2/c1-10-14-6-29(9-19(10,14)28-17(31)13-2-20(13,22)23)16-15(21)4-24-18(27-16)26-11-3-25-30(5-11)12-7-32-8-12/h3-5,10,12-14H,2,6-9H2,1H3,(H,28,31)(H,24,26,27)/t10-,13+,14+,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 M...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35J0
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM330016 (US10463675, Example 99 | US10980815, Ex. No. 99 | ...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@]12NC(=O)[C@@H]1CC1(F)F)c1nc(Nc2cnn(c2)C2COC2)ncc1F |r| Show InChI InChI=1S/C20H22F3N7O2/c1-10-14-6-29(9-19(10,14)28-17(31)13-2-20(13,22)23)16-15(21)4-24-18(27-16)26-11-3-25-30(5-11)12-7-32-8-12/h3-5,10,12-14H,2,6-9H2,1H3,(H,28,31)(H,24,26,27)/t10-,13+,14+,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...				US Patent US10980815 (2021) BindingDB Entry DOI: 10.7270/Q2XD14SG
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM330016 (US10463675, Example 99 | US10980815, Ex. No. 99 | ...) Show SMILES C[C@@H]1[C@@H]2CN(C[C@]12NC(=O)[C@@H]1CC1(F)F)c1nc(Nc2cnn(c2)C2COC2)ncc1F |r| Show InChI InChI=1S/C20H22F3N7O2/c1-10-14-6-29(9-19(10,14)28-17(31)13-2-20(13,22)23)16-15(21)4-24-18(27-16)26-11-3-25-30(5-11)12-7-32-8-12/h3-5,10,12-14H,2,6-9H2,1H3,(H,28,31)(H,24,26,27)/t10-,13+,14+,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...				US Patent US10463675 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VGN
					More data for this Ligand-Target Pair