Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM455543'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM455543 ((R)-3-(4-(4-(1-((R)-1,1,1-trifluoropentan-3-yl)-1H...) Show SMILES CCC(CC(F)(F)F)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C20H22F3N7O2/c1-2-15(5-20(21,22)23)29-9-14(7-26-29)19-18-3-4-24-30(18)11-17(27-19)13-6-25-28(8-13)10-16(32)12-31/h3-4,6-9,11,15-16,31-32H,2,5,10,12H2,1H3/t15?,16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020) BindingDB Entry DOI: 10.7270/Q2CC13R9
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM455543 ((R)-3-(4-(4-(1-((R)-1,1,1-trifluoropentan-3-yl)-1H...) Show SMILES CCC(CC(F)(F)F)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C20H22F3N7O2/c1-2-15(5-20(21,22)23)29-9-14(7-26-29)19-18-3-4-24-30(18)11-17(27-19)13-6-25-28(8-13)10-16(32)12-31/h3-4,6-9,11,15-16,31-32H,2,5,10,12H2,1H3/t15?,16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021) BindingDB Entry DOI: 10.7270/Q2T156RN
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM455543 ((R)-3-(4-(4-(1-((R)-1,1,1-trifluoropentan-3-yl)-1H...) Show SMILES CCC(CC(F)(F)F)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C20H22F3N7O2/c1-2-15(5-20(21,22)23)29-9-14(7-26-29)19-18-3-4-24-30(18)11-17(27-19)13-6-25-28(8-13)10-16(32)12-31/h3-4,6-9,11,15-16,31-32H,2,5,10,12H2,1H3/t15?,16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020) BindingDB Entry DOI: 10.7270/Q2CC13R9
					More data for this Ligand-Target Pair