BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nonstructural protein 3' and Ligand = 'BDBM50567466'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nonstructural protein 3 (Zika virus)	BDBM50567466 (CHEMBL4862682) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Charles University Prague Curated by ChEMBL					Assay Description Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicans				Bioorg Med Chem 18: 1434-40 (2010) Article DOI: 10.1016/j.bmc.2010.01.015
Charles University Prague Curated by ChEMBL					More data for this Ligand-Target Pair
Nonstructural protein 3 (Zika virus)	BDBM50567466 (CHEMBL4862682) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition Zika virus NS3B (47 to 95 residues)/NS3 (1 to 170 residues) protease expressed in Escherichia coli BL21 using 7-amino-4-methylcoumarin as ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02070 BindingDB Entry DOI: 10.7270/Q20G3PWH
TBA					More data for this Ligand-Target Pair