Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50044152'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50044152 (CHEMBL3314027) Show SMILES Cc1ccc([C@@H](NC(=O)Cc2ccc3oc(cc3c2)C(N2CC(N)C2)c2ccncc2)c2ccccc2)c(C)c1 |r| Show InChI InChI=1S/C34H34N4O2/c1-22-8-10-29(23(2)16-22)33(25-6-4-3-5-7-25)37-32(39)18-24-9-11-30-27(17-24)19-31(40-30)34(38-20-28(35)21-38)26-12-14-36-15-13-26/h3-17,19,28,33-34H,18,20-21,35H2,1-2H3,(H,37,39)/t33-,34?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitment				J Med Chem 57: 5871-92 (2014) Article DOI: 10.1021/jm401901d BindingDB Entry DOI: 10.7270/Q2M0473Z
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