Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50108886'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108886 (CHEMBL3596603) Show SMILES Fc1cccc(Cl)c1C(=O)N1CCCc2cc(ccc12)-c1cc(ccc1Cl)C(=O)NC1CCCC1 Show InChI InChI=1S/C28H25Cl2FN2O2/c29-22-12-10-19(27(34)32-20-6-1-2-7-20)16-21(22)17-11-13-25-18(15-17)5-4-14-33(25)28(35)26-23(30)8-3-9-24(26)31/h3,8-13,15-16,20H,1-2,4-7,14H2,(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108886 (CHEMBL3596603) Show SMILES Fc1cccc(Cl)c1C(=O)N1CCCc2cc(ccc12)-c1cc(ccc1Cl)C(=O)NC1CCCC1 Show InChI InChI=1S/C28H25Cl2FN2O2/c29-22-12-10-19(27(34)32-20-6-1-2-7-20)16-21(22)17-11-13-25-18(15-17)5-4-14-33(25)28(35)26-23(30)8-3-9-24(26)31/h3,8-13,15-16,20H,1-2,4-7,14H2,(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at Gal4 DNA binding domain-tagged human RORgammat expressed in HEK293T cells assessed as effect on receptor-mediated transcr...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair