Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50108890'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108890 (CHEMBL3596612) Show SMILES CC1(C)CCN(C(=O)c2c(F)cccc2Cl)c2ccc(cc12)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C25H21Cl2FN2O2/c1-25(2)10-11-30(24(32)22-19(27)4-3-5-20(22)28)21-9-7-14(13-17(21)25)16-12-15(23(29)31)6-8-18(16)26/h3-9,12-13H,10-11H2,1-2H3,(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108890 (CHEMBL3596612) Show SMILES CC1(C)CCN(C(=O)c2c(F)cccc2Cl)c2ccc(cc12)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C25H21Cl2FN2O2/c1-25(2)10-11-30(24(32)22-19(27)4-3-5-20(22)28)21-9-7-14(13-17(21)25)16-12-15(23(29)31)6-8-18(16)26/h3-9,12-13H,10-11H2,1-2H3,(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at Gal4 DNA binding domain-tagged human RORgammat expressed in HEK293T cells assessed as effect on receptor-mediated transcr...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair