Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50108901'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108901 (CHEMBL3596616) Show SMILES CN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C21H15Cl2FN2O2/c1-26(21(28)19-17(23)3-2-4-18(19)24)14-8-5-12(6-9-14)15-11-13(20(25)27)7-10-16(15)22/h2-11H,1H3,(H2,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
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