Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50108911'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108911 (CHEMBL3596594) Show SMILES COc1ccc(cc1-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl)C(N)=O Show InChI InChI=1S/C24H20ClFN2O3/c1-31-21-10-8-16(23(27)29)13-17(21)14-7-9-20-15(12-14)4-3-11-28(20)24(30)22-18(25)5-2-6-19(22)26/h2,5-10,12-13H,3-4,11H2,1H3,(H2,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
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