Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50108925'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50108925 (CHEMBL3596614) Show SMILES NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCOc2c1)C(=O)c1c(F)cccc1Cl Show InChI InChI=1S/C22H15Cl2FN2O3/c23-15-6-4-13(21(26)28)10-14(15)12-5-7-18-19(11-12)30-9-8-27(18)22(29)20-16(24)2-1-3-17(20)25/h1-7,10-11H,8-9H2,(H2,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) Article DOI: 10.1016/j.bmcl.2015.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47XQ
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