Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50203507'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50203507 (CHEMBL3915908) Show SMILES CN(C)C(=O)c1ccc2n(nc(Nc3c(Cl)cccc3Cl)c2c1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H18Cl2N4O3/c1-28(2)22(30)14-8-11-19-16(12-14)21(26-20-17(24)4-3-5-18(20)25)27-29(19)15-9-6-13(7-10-15)23(31)32/h3-12H,1-2H3,(H,26,27)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Galderma R&D Curated by ChEMBL					Assay Description Inverse agonist activity at GAL4 DBD-fused RORgammat LBD (unknown origin) expressed in HG5LN cells after 18 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 26: 5802-5808 (2016) Article DOI: 10.1016/j.bmcl.2016.10.023 BindingDB Entry DOI: 10.7270/Q2D79DDH
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