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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [258-518,Y502F]' and Ligand = 'BDBM231224'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma [258-518,Y502F]


(Artificial Sequence)		BDBM231224
PNG
(US9346782, 4)
Show SMILES CCCCC(O)(c1cncn1C)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1
Show InChI InChI=1S/C24H23Cl2N3O/c1-3-4-12-24(30,20-14-27-15-29(20)2)17-10-11-19-18(13-17)22(25)21(23(26)28-19)16-8-6-5-7-9-16/h5-11,13-15,30H,3-4,12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.50E+3n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...

US Patent US9346782 (2016)


BindingDB Entry DOI: 10.7270/Q2DB80PS
More data for this
Ligand-Target Pair