Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nucleotide-binding oligomerization domain-containing protein 2' and Ligand = 'BDBM50056689'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056689 (CHEMBL3326922) Show SMILES CCCCCn1c(NC(C)=O)nc2ccccc12 Show InChI InChI=1S/C14H19N3O/c1-3-4-7-10-17-13-9-6-5-8-12(13)16-14(17)15-11(2)18/h5-6,8-9H,3-4,7,10H2,1-2H3,(H,15,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair