Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'OTU domain-containing protein 7B' and Ligand = 'BDBM443298'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443298 ((S)-7-(3- Cyanophenyl)- 2-oxo-1,2- dihydrospiro [p...) Show SMILES O=C1Nc2cc(cnc2O[C@]11CCN(C1)C#N)-c1cccc(c1)C#N |r| Show InChI InChI=1S/C18H13N5O2/c19-8-12-2-1-3-13(6-12)14-7-15-16(21-9-14)25-18(17(24)22-15)4-5-23(10-18)11-20/h1-3,6-7,9H,4-5,10H2,(H,22,24)/t18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443298 ((S)-7-(3- Cyanophenyl)- 2-oxo-1,2- dihydrospiro [p...) Show SMILES O=C1Nc2cc(cnc2O[C@]11CCN(C1)C#N)-c1cccc(c1)C#N |r| Show InChI InChI=1S/C18H13N5O2/c19-8-12-2-1-3-13(6-12)14-7-15-16(21-9-14)25-18(17(24)22-15)4-5-23(10-18)11-20/h1-3,6-7,9H,4-5,10H2,(H,22,24)/t18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair