Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'OTU domain-containing protein 7B' and Ligand = 'BDBM443330'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443330 (6'-(6-Methoxypyridin-3-yl)-2'-oxo- 1',4'-dihydro-2...) Show SMILES COc1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C19H18N4O2/c1-25-17-5-3-14(10-21-17)13-2-4-16-15(8-13)9-19(18(24)22-16)6-7-23(11-19)12-20/h2-5,8,10H,6-7,9,11H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443330 (6'-(6-Methoxypyridin-3-yl)-2'-oxo- 1',4'-dihydro-2...) Show SMILES COc1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C19H18N4O2/c1-25-17-5-3-14(10-21-17)13-2-4-16-15(8-13)9-19(18(24)22-16)6-7-23(11-19)12-20/h2-5,8,10H,6-7,9,11H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443330 (6'-(6-Methoxypyridin-3-yl)-2'-oxo- 1',4'-dihydro-2...) Show SMILES COc1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C19H18N4O2/c1-25-17-5-3-14(10-21-17)13-2-4-16-15(8-13)9-19(18(24)22-16)6-7-23(11-19)12-20/h2-5,8,10H,6-7,9,11H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair