Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM184125'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM184125 (US9150566, 163) Show SMILES C[C@@H]1OCCN([C@@H]1Cc1cccc(c1)-n1nccn1)C(=O)c1ccc(C)cc1-n1nccn1 Show InChI InChI=1S/C24H25N7O2/c1-17-6-7-21(23(14-17)31-27-10-11-28-31)24(32)29-12-13-33-18(2)22(29)16-19-4-3-5-20(15-19)30-25-8-9-26-30/h3-11,14-15,18,22H,12-13,16H2,1-2H3/t18-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9150566 (2015) BindingDB Entry DOI: 10.7270/Q2M32TJ3
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