Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM208491'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM208491 (US9266870, 7) Show SMILES C[C@@H]1CO[C@@H](Cn2ccc(n2)-c2ccc(F)cn2)N1C(=O)c1cc(C)ccc1-n1nccn1 |r| Show InChI InChI=1S/C23H22FN7O2/c1-15-3-6-21(31-26-8-9-27-31)18(11-15)23(32)30-16(2)14-33-22(30)13-29-10-7-20(28-29)19-5-4-17(24)12-25-19/h3-12,16,22H,13-14H2,1-2H3/t16-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
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