Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM208511'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM208511 (US9266870, 27) Show SMILES Cc1ccc(c(n1)C(=O)N1CCOC1Cn1ccc(n1)-c1ccc(F)cc1)-n1nccn1 Show InChI InChI=1S/C22H20FN7O2/c1-15-2-7-19(30-24-9-10-25-30)21(26-15)22(31)29-12-13-32-20(29)14-28-11-8-18(27-28)16-3-5-17(23)6-4-16/h2-11,20H,12-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
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