Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM208512'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM208512 (US9266870, 28) Show SMILES Cc1ccc(c(n1)C(=O)N1CCCOC1Cn1ccc(n1)-c1ccc(F)cc1)-n1nccn1 Show InChI InChI=1S/C23H22FN7O2/c1-16-3-8-20(31-25-10-11-26-31)22(27-16)23(32)30-12-2-14-33-21(30)15-29-13-9-19(28-29)17-4-6-18(24)7-5-17/h3-11,13,21H,2,12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
					More data for this Ligand-Target Pair