Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 325 | -38.9 | n/a | n/a | n/a | n/a | n/a | n/a | 40 |
JANSSEN PHARMACEUTICA NV US Patent | Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F... | US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 325 | -38.9 | n/a | n/a | n/a | n/a | n/a | n/a | 40 |
Janssen Pharmaceutica NV US Patent | Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ... | US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 325 | -38.9 | n/a | n/a | n/a | n/a | n/a | n/a | 40 |
JANSSEN PHARMACEUTICA NV US Patent | Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%... | US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 325 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ... | US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 336 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ... | US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68 | |||||||||||
More data for this Ligand-Target Pair |