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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM184003'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))
BDBM184003
PNG
(US9150566, 40)
Show SMILES Cc1ccnc(n1)-c1cccc(C[C@@H]2COCCN2C(=O)c2ccccc2-n2nccn2)c1
Show InChI InChI=1S/C25H24N6O2/c1-18-9-10-26-24(29-18)20-6-4-5-19(15-20)16-21-17-33-14-13-30(21)25(32)22-7-2-3-8-23(22)31-27-11-12-28-31/h2-12,15,21H,13-14,16-17H2,1H3/t21-/m1/s1
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Similars

US Patent
n/an/a 762n/an/an/an/an/a37



ACTELION PHARMACEUTICALS LTD.

US Patent


Assay Description
Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...


US Patent US9150566 (2015)


BindingDB Entry DOI: 10.7270/Q2M32TJ3
More data for this
Ligand-Target Pair