Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM184095'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM184095 (US9150566, 133) Show SMILES COc1ccc(c(C(=O)N2CCOC[C@H]2Cc2cc(ccc2F)-n2nccn2)c1F)-n1nccn1 Show InChI InChI=1S/C23H21F2N7O3/c1-34-20-5-4-19(32-28-8-9-29-32)21(22(20)25)23(33)30-10-11-35-14-17(30)13-15-12-16(2-3-18(15)24)31-26-6-7-27-31/h2-9,12,17H,10-11,13-14H2,1H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9150566 (2015) BindingDB Entry DOI: 10.7270/Q2M32TJ3
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