Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM208498'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM208498 (US9266870, 14) Show SMILES Cc1ccc(c(c1)C(=O)N1CCOC1Cn1ccc(n1)-c1ccc(F)cn1)-c1ncccn1 |w:13.15| Show InChI InChI=1S/C24H21FN6O2/c1-16-3-5-18(23-26-8-2-9-27-23)19(13-16)24(32)31-11-12-33-22(31)15-30-10-7-21(29-30)20-6-4-17(25)14-28-20/h2-10,13-14,22H,11-12,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
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