Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM221368'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM221368 (US9303023, 64) Show SMILES COc1ccc2ncn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2c1 Show InChI InChI=1S/C24H22N6O3/c1-16-4-3-5-17(10-16)23-22(26-15-33-23)24(31)28-18-12-27-30(13-18)9-8-29-14-25-20-7-6-19(32-2)11-21(20)29/h3-7,10-15H,8-9H2,1-2H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9303023 (2016) BindingDB Entry DOI: 10.7270/Q2251H10
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