Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM335275'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM335275 (US11040966, Example 6.47 | US9732075, Example 6.47...) Show SMILES Cc1nc(C(=O)N2CC(=C)C[C@H]2c2nc3c(C)c(C)ccc3[nH]2)c(s1)-c1ccc(C)c(C)c1 Show InChI InChI=1S/C27H28N4OS/c1-14-11-22(26-29-21-10-8-16(3)18(5)23(21)30-26)31(13-14)27(32)24-25(33-19(6)28-24)20-9-7-15(2)17(4)12-20/h7-10,12,22H,1,11,13H2,2-6H3,(H,29,30)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
IDORSIA PHARMACEUTICALS LTD US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9732075 (2017) BindingDB Entry DOI: 10.7270/Q29P33S0
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