BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50355799'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))
BDBM50355799
PNG
(CHEMBL1911744)
Show SMILES C[C@@H]1COc2ccc(cc2[C@H](C)N1C(=O)c1ccc(Cl)cc1)S(C)(=O)=O |r|
Show InChI InChI=1S/C19H20ClNO4S/c1-12-11-25-18-9-8-16(26(3,23)24)10-17(18)13(2)21(12)19(22)14-4-6-15(20)7-5-14/h4-10,12-13H,11H2,1-3H3/t12-,13+/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company

Curated by ChEMBL


Assay Description
Antagonist activity at human OX2R expressed in CHO cells assessed intracellular calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 21: 6414-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.093
BindingDB Entry DOI: 10.7270/Q2BZ66DH
More data for this
Ligand-Target Pair