Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orf1a protein (MERS-CoV) | BDBM448319![]() (GC-376 | GC376) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Arizona | Assay Description Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre... | ACS Pharmacol Transl Sci 4: 1408-1421 (2021) Article DOI: 10.1021/acsptsci.1c00099 BindingDB Entry DOI: 10.7270/Q20V8GWQ | |||||||||||
More data for this Ligand-Target Pair |